Children Who Survive Congenital Heart Defects Can Face New Problems As AdultsIt was a medical miracle: Surgery that made it possible for babies born with heart defects to live to adulthood. But for some, those mended hearts start to falter decades later. Jan 28 18January 28, 2018Article at npr.org
I Thought It Was Just Stress, Until It Broke My HeartSure, she felt sick, but it was probably just stress. She had to make it to the crucial meeting at her son's school and solve the day care problem. But all along her heart was whispering, "enough." Sep 27 14September 27, 2014Article at npr.org
John Rummel Protects All of the Planets, All of the TimeJohn Rummel, NASA's planetary protection officer, works to protect alien life from us Feb 20 26February 20, 2026PDF at Red Herring
Around The World, When It Comes To Health Advice Mom Knows BestIn the U.S., VapoRub goes on a sick child's chest. In Russia, it might go on the soles of the feet. Cultural norms have a big effect on how we diagnose and treat illnesses, especially at home. Jun 19 16June 19, 2016Article at npr.org
A Young Man With A Disability Goes Missing: How Do You Find Him?Zachary Briley's family found out that even though he was developmentally disabled, his disappearance was not classified as an emergency. Laws that protect adults' rights can make searches difficult. Mar 20 16March 20, 2016Article at npr.org
Before Zika Virus, Rubella Was A Pregnant Woman's NightmareOur experience with the rubella virus, which can cause miscarriages or serious birth defects if a woman gets infected while pregnant, may help scientists figure out how to combat Zika virus. Jan 30 16January 30, 2016Article at npr.org
When You've Got The Blues, You Have A Hard Time Seeing BluePeople who are sad have a harder time seeing yellow and blue, an experiment finds, but they can see green and red just fine. It might have something to do with dopamine receptors in the brain. Sep 05 15September 05, 2015Article at npr.org
Are Statins Bad For Me? Personalized Medicine Can't Yet SayStatins made her feel wretched, so she took a DNA test to find out why. But even the doctor with the genetic testing company admits that the test doesn't tell you much more than you already know. Sep 01 15September 01, 2015Article at npr.org
Playing The Odds With Statins: Heart Disease Or Diabetes?Doctors hand out cholesterol-lowering statins like breath mints, but like any drug they come with risks. Less heart disease, sure, a slightly higher risk of diabetes, too. So what's a person to do? Mar 10 15March 10, 2015Article at npr.org
Ariad Pharmaceutical’s Ninja Cancer Drug Inhibits Armies of MutantsOn a Friday afternoon in 2009, Hans Loland was battling his insurance company to get into a phase I trial for ponatinib, an investigational drug for chronic myeloid leukemia (CML) developed by Ariad Pharmaceuticals, Inc. (http://www.ariad.com). Loland, in his early 40s and an analyst for Microsoft, was to begin preparations for a bone marrow transplant the following Monday. He had failed first-line treatment with imatinib mesylate (Gleevec) and had spent three months on dasatinib (Sprycel), a se Sep 21 12September 21, 2012Article at cell.com
Targacept's NNR Drugs Rehabilitate NicotineTobacco has been used for centuries despite its health risks. Cigarettes are hard to quit because they deliver nicotine, a potent and addictive drug, along with “tar.” But now nicotine is angling for redemption in the form of a new class of CNS drugs targeting neuronal nicotinic receptors (NNRs) also known as neuronal acetylcholine nicotinic receptors (nAChRs), which modulate the flow of neurotransmitters throughout the brain and nervous system. Jan 29 10January 29, 2010Article at cell.com
caBIG: Seeking Cancer Cures by Bits and BytesWhile our understanding of cancer is becoming increasingly nuanced, we still don't know why some people get certain cancers and others do not, nor why cancers behave differently in some patients. “Virtually every man will get prostate cancer if he lives long enough.” says David Steffen, Ph.D., director, Bioinformatics Research, Department of Molecular and Human Genetics at Baylor University. “For most it isn't serious. For a few it is.” According to Steffen, even with a careful statistical study Jun 23 08June 23, 2008Article at cell.com
Neuropathic Pain Treatment Gives Avigen New Lease on Life and Neuromed Follows the Snail TrailPain is one of the body's main warning systems, but when nerves malfunction, they may spontaneously amplify benign stimuli such as heat, cold, and light pressure, generating pain signals. This becomes a debilitating condition known as neuropathic pain, usually associated with nerve trauma or diseases such as diabetic neuropathy, multiple sclerosis, viral infections, or the course of cancer chemotherapy. It can also follow injury to the spinal cord or damage from a stroke. Recent studies suggest Apr 20 07April 20, 2007Article at cell.com
Leapin' Lizards: Amylin Targets Diabetes and Obesity via IncretinsDiabetes mellitus is a progressive disorder that prevents the body from effectively regulating blood glucose levels. Patients with Type II diabetes either do not make enough insulin or become resistant to it. In contrast, Type I diabetes, otherwise known as juvenile diabetes, is an autoimmune disease in which an individual loses the ability to produce insulin. Mar 01 07March 01, 2007Article at cell.com
Boston Autism Consortium Searches for Genetic Clues to Autism's PuzzleAutism has received considerable attention in the past few years; some say its incidence is increasing. Upon closer examination, however, the picture blurs. A nascent initiative in Boston, the Boston Autism Consortium, may represent a pragmatic model for dealing with complex diseases, one that involves different institutions collaborating rather than competing and applying research directly to patient care. Feb 01 07February 01, 2007Article at cell.com
Ablynx Makes Nanobodies from Llama BodiesAntibodies, the sentinels of the immune system, are “Y” shaped, globular proteins with sites that bind to specific antigens. Antibodies are produced by B lymphocytes in response to stimulation by an antigen. Antibodies are versatile; they can bind to proteins, nucleic acids, carbohydrates, and lipids, making them eminently useful in the development of diagnostics and drugs for the treatment of autoimmune, inflammatory, and infectious diseases, as well as cancers. Dec 01 06December 01, 2006Article at cell.com
Speedel Staunches the Renin Cascade at Its SourceHypertension gives no warning signs. Left untreated, it can lead to kidney and heart disease, retinal damage, and stroke. Its root causes are mostly unknown. About 190 million people in developed countries suffer from hypertension. The American Heart Association estimates nearly one in three U.S. adults have high blood pressure and that over a third of them do not effectively control it. Nov 01 06November 01, 2006Article at cell.com