Tony Romo, QB, Dallas (at Arizona): Romo has thrown multiple TDs in four straight games.
LeGarrette Blount, RB, Tampa Bay (vs. Carolina): The Panthers have allowed at least 80 yards to a running back in all but one game.
Mark Ingram, RB, New Orleans (vs. Detroit): The Lions are ranked 23rd vs. the run and will be without defensive tackle Ndamukong Suh.
Victor Cruz, WR, Giants (vs. Green Bay): Cruz is averaging 112 yards in his past five games. The Packers' pass D allows 288 yards a game.
Dwayne Bowe, WR, Kansas City (at Chicago): The Bears are ranked 30th against the pass.
Jake Ballard, TE, Giants (vs. Green Bay): Only the Cowboys have allowed more yards to tight ends than the Packers have.
Dallas defense (at Arizona): The Cardinals turn the ball over often and give up plenty of sacks.
Philip Rivers, QB, San Diego (at Jacksonville): The Jags allow 183 yards per game through the air, fourth fewest in the NFL.
Rashard Mendenhall, RB, Pittsburgh (vs. Cincinnati): Mendenhall has topped 70 yards rushing just once, and the Bengals are fifth vs. the run.
Steven Jackson, RB, St. Louis (at San Francisco): The 49ers have not allowed more than 64 yards to any running back.
Anquan Boldin, WR, Baltimore (at Cleveland): The Browns give up a league-low 174.7 passing yards per game.
Santonio Holmes, WR, Jets (at Washington): Holmes has been held to less than 40 yards in four of his past five games.
Vernon Davis, TE, San Francisco (vs. St. Louis): The Rams allow the fewest fantasy points to tight ends.
Detroit defense (at New Orleans): The Saints average 41.2 points at home.